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Tool Catalogue

ARCHIMEDES provides access to a growing collection of analysis tools. This catalogue highlights a selection of commonly used tools to help you get started.

ℹ️Note: The Tool Catalogue is continuously expanding. Additional tools, including cardiac imaging analysis tools, will be added as they become available. If you are interested in a specific analysis tool, please contact us at ARCHIMEDES@ottawaheart.ca.

File Format Conversion

Tools for converting research data between commonly used medical imaging and neuroimaging file formats.

Tool Description
Dcm2mnc Converts DICOM images to the MINC file format.
Dcm2nii Converts DICOM images to the NIfTI file format.
Dicom2hrrt Converts DICOM PET images to the HRRT file format.
Minc2analyze Converts MINC images to the Analyze file format.
Minc2jiv Converts MINC images for visualization in the JIV viewer.
MincConvert Converts MINC images between supported MINC formats.
Mnc2nii Converts MINC images to the NIfTI file format.
Nii2mnc Converts NIfTI images to the MINC file format.

File Operations

Tools for extracting files from existing datasets.

Tool Description
SimpleFileExtractor Extracts files from existing datasets by matching specified filename patterns.

Structural MRI

Tools for processing and and analyzing brain anatomy and structural images.This includes cortical surfaces, tissue segmentation, and quality control.

Tool Description
BigBrainWarp Maps neuroimaging data to the BigBrain anatomical atlas for advanced brain mapping and analysis.
CIVET Processes structural MRI data to generate cortical surface models and measure cortical thickness.
CIVET QC Tool Performs quality control on CIVET processing outputs to help assess data quality.
CivetCombiNer Combines outputs from multiple CIVET processing steps into a unified dataset.
Civetmacaque Processes structural MRI data from macaque brains using the CIVET pipeline.
csv_Neocivet Processes neonatal structural MRI data using the NeoCIVET pipeline.
FreeSurferRecoNAll Performs automated cortical surface reconstruction and anatomical segmentation using FreeSurfer.
Fsl_aNat Performs automated preprocessing of structural MRI data using FSL.
FslFast Segments brain tissue into gray matter, white matter, and cerebrospinal fluid.
FSLFirst Segments subcortical brain structures from structural MRI images.
hippunfold Segments and analyzes the hippocampus using structural MRI data.
NuCorrect Corrects intensity non-uniformity (bias field) in MRI images.
ReconAll Runs the standard FreeSurfer pipeline for structural MRI analysis.
ReconAllLongi Performs longitudinal structural MRI analysis across multiple time points using FreeSurfer.

Functional MRI (fMRI) Analysis & Preprocessing

Tools for preprocessing (preparing and cleaning), analyzing, and visualizing functional MRI (fMRI) data to study brain activity and functional connectivity.

Tool Description
FMRIprepBidsSubject Preprocesses BIDS-formatted functional MRI datasets using the fMRIPrep workflow.
FslFeat Performs statistical analysis of functional MRI data using the FSL FEAT pipeline.
FslFlirt Registers and aligns functional and structural MRI images.
FslMelodic Performs independent component analysis (ICA) to identify functional brain networks.
ICA_AROMA Identifies and removes motion-related artifacts from functional MRI data.
McFlirt Corrects head motion in functional MRI time series.
MICAPE Processes multimodal MRI data using the MICAPE workflow.
TAPAS PhysIO Models and corrects physiological noise in functional MRI data.
melodic Performs independent component analysis (ICA) to identify functional brain networks.

Tractography (Diffusion MRI)

Tools for processing and analyzing diffusion MRI data to map white matter pathways and assess brain connectivity.

Tool Description
FslBedpostx Estimates diffusion parameters and fiber orientations for diffusion MRI analysis.
ndmg Processes diffusion MRI data to generate structural brain connectivity networks.

Arterial Spin Labeling (ASL)

Tools for processing and analyzing Arterial Spin Labeling (ASL) MRI data to measure tissue perfusion and cerebral blood flow

Tool Description
ASLPrep Preprocesses ASL MRI data using a standardized workflow for perfusion imaging analysis.
oxford_asl Quantifies cerebral blood flow and other perfusion measures from ASL MRI data.

PET

Tools for processing and analyzing Positron Emission Tomography (PET) data.

Tool Description
APPIANPET Processes and analyzes PET imaging data using the APPIAN PET analysis pipeline.

EEG / MEG

Tools for processing and analyzing electroencephalography (EEG) data to support the study of brain electrical activity.

Tool Description
Brainstorm Processes, analyzes, and visualizes EEG and MEG data.
HarMNqEEG Harmonizes and analyzes quantitative EEG (qEEG) data across studies.
qEEG Analyzes quantitative EEG data to assess brain activity and function.

Brain Lesion Segmentation

Tools for identifying, segmenting, and analyzing brain lesions from medical imaging data.

Tool Description
BraTSPipeline Segments and analyzes brain tumors and lesions from MRI data using the BraTS workflow.
lesionBrain Automatically identifies and segments brain lesions from MRI images.

Neuroimaging Processing Tools

Tools for processing and analyzing neuroimaging data.

Tool Description
FslBet Removes non-brain tissue from MRI images using FSL's Brain Extraction Tool (BET).
Mincmath Performs mathematical operations on MINC image files.
Mincresample Resamples MINC images to modify their resolution, orientation, or spatial dimensions.

Statistical Analysis

Tools for performing statistical analysis of research data.

Tool Description
FslRandomise Performs non-parametric statistical analysis of neuroimaging data using permutation testing.
Fslstats Calculates statistical measures from neuroimaging data.
Mincaverage Computes the average of multiple MINC image files.
Mincpik Generates image previews from MINC files for visualization and quality assessment.

Genetics

Tools for processing and analyzing genetic data.

Tool Description
Biomarkers Identifies and analyzes genetic biomarkers associated with biological processes and disease.
cellranger-count Processes single-cell sequencing data by aligning reads, counting gene expression, and generating feature-barcode matrices.

Genomics

Tools for processing and analyzing genomic data.

Tool Description
ePRS_5HTT Calculates expression-based polygenic risk scores (ePRS) related to the serotonin transporter (5-HTT) pathway.
imputePrepSanger Prepares genotype data for imputation using the Sanger Imputation Service.
MethylationPipeliNe Processes and analyzes DNA methylation data.
mfannot Annotates mitochondrial genome sequences and identifies genomic features.

Pipeline Development

Tools for developing, packaging, and managing analysis pipelines.

Tool Description
BoutiquesDescriptorMaker Creates Boutiques descriptors for packaging and describing analysis tools to support reproducible execution across computing platforms.